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New Books


Pharmacodynamic Basis of Herbal Medicine
Added 3/19/2008
Manuchair Ebadi
MEDICINAL HERBS ALSO HAVE A USEFULNESS BEYOND WHAT THEIR OVER-THE-COUNTER FORMS PROVIDE

Pharmacodynamic Basis of Herbal Medicine gives you a better understanding of how natural products:

  • Provide a number of extremely useful drugs that are difficult, if not impossible, to produce commercially by synthetic means
  • Supply basic compounds that may be modified slightly to render them more effective or less toxic
  • Are useful as prototypes or models for synthetic drugs possessing physiologic activities similar to the original drug
  • Contain compounds that demonstrate little or no activity themselves but which can be modified by chemical or biological methods to produce potent drugs not easily obtained by other methods
REDUCE UNWANTED SIDE EFFECTS AND ENHANCE THERAPEUTIC EFFICACY

Whether they take herbal medicine for religious, philosophical, or economic reasons, Western believers are just discovering what Eastern civilizations have known for centuries. As the use of herbal remedies grows exponentially, so too does the necessity for information on how these herbs actually work. Author Manuchair Ebadi, winner of the 2004 University of North Dakota Foundation Thomas J. Clifford Faculty Achievement Award for Excellence in Research, builds the scientific bridge between Eastern and Western medicine. For a multitude of popularly used herbs it demonstrates the beneficial effects and adverse side effects of herbal drugs, showing their actions and effects on organ, tissue, cellular, and subcellular levels. By understanding and applying the information in this book, you will be able to provide safer and more effective therapeutic care.



Inorganic Materials Chemistry Desk Reference, Second Edition
Added 12/14/2007
D. SangeetaJohn R LaGraff
  • Provides a major update and expansion of the topics covered in the first edition
  • Adds over 200 new definitions
  • Documents 50% more new chemical precursors and their properties
  • Includes anisotropic properties of single crystal materials in material properties chapter
  • Emphasizes new applications of inorganic materials
  • Discusses new topics such as combinatorial chemistry, nanostructures, and biomaterials

The updated second edition of the popular Inorganic Materials Chemistry Desk Reference remains a valuable resource in the preparation of solid-state inorganic materials by chemical processing techniques. It also expands upon new chemical precursors available to materials scientists, the applications of those materials, and existing or emerging topics where materials chemistry plays an important role, such as in microelectronics, surface science, and nanotechnology.

This edition places additional emphasis on additives, characterization techniques and structure-property relationships, and materials classifications based on type and applications, including electronics, biomaterials, thin films, and coatings. Other new topics include combinatorial chemistry, nanostructures and technology, surface materials chemistry, biomimetic processing, and novel forms of carbon. The authors discuss the role of materials chemistry in micro- and nano-fabrication, self-assembly, scanning probe microscopy, and carbon fullerenes.

The new edition adds forty black and white figures, over 200 new definitions, and 50% more new chemical precursors and their properties. With a new and improved reference format, Inorganic Materials Chemistry Desk Reference continues to be a constructive resource to specialists conducting research in materials chemistry.



Powder Technology Handbook, Third Edition
Added 3/21/2008
Hiroaki MasudaKo HigashitaniHideto Yoshida
The Powder Technology Handbook, Third Edition provides a comprehensive guide to powder technology while examining the fundamental engineering processes of particulate technology. The book offers a well-rounded perspective on powder technologies that extends from particle to powder and from basic problems to actual applications.

Providing comprehensive coverage of powder/particle handling methods and unit operations, this handbook prepares the reader for solving new problems using an integrated approach. By presenting problems in wet processes and particles in liquids alongside those encountered with dry powder processes, it offers strategies for finding the optimal solutions to problems in any context. The book contains new sections on particle motion in fluids, design and formulation of composite particles, combustion and heating, electrostatic powder coating, attrition of a particle, breakage of aggregates, and the particle motion, rheology, and electrical properties of a powder bed. It also discusses recently developed areas of study such as simulation, surface analysis, and nanoparticles.

Maintaining the standard of quality found in the previous bestselling editions, the third edition of the Powder Technology Handbook reflects the most recent advances and provides convenient access to processes and properties of particulate technology.

Biocatalysis in the Pharmaceutical and Biotechnology Industries
Added 1/11/2008
Ramesh Patel
Because enzyme-catalyzed reactions exhibit higher enantioselectivity, regioselectivity, substrate specificity, and stability, they require mild conditions to react while prompting higher reaction efficiency and product yields. Biocatalysis in the Pharmaceutical and Biotechnology Industries examines the use of catalysts to produce fine chemicals and chiral intermediates in a variety of pharmaceutical, agrochemical, and other biotechnological applications.

Written by internationally recognized scientists in biocatalysis, the authors analyze the synthesis of chiral intermediates for over 60 brand-name pharmaceuticals for a wide range of drug therapies and treatments. From starting material to product, the chapters offer detailed mechanisms that show chiral intermediates and other by-products for each reaction-including hydrolytic, acylation, halogenation, esterification, dehalogenation, oxidation-reduction, oxygenation, hydroxylation, deamination, transamination, and C-C, C-N, C-O bonds formation. Cutting-edge topics include advanced methodologies for gene shuffling and directed evolution of biocatalysts; the custom engineering of enzymes; the use of microbial cells and isolated biocatalysts; the use of renewable starting materials; and generating novel molecules by combinatorial biocatalysis and high-throughput screening.

Focusing on industrial applications, the book also considers factors such as bulk processes, instrumentation, solvent selection, and techniques for catalyst immobilization, reusability, and yield optimization throughout. Biocatalysis in the Pharmaceutical and Biotechnology Industries showcases the practical advantages and methodologies for using biocatalysts to develop and produce chiral pharmaceuticals and fine chemicals.

Powders and Fibers: Interfacial Science and Applications
Added 12/14/2007
Michel NardinEugene Papirer
New analytical methods have provided further insight into the structure, surface characteristics, and chemistries of increasingly small particles. However, current literature offers information on only a limited number of powders being investigated. Written by renowned scientists in the field, Powders and Fibers: Interfacial Science and Applications examines the most appropriate characterization methods for analyzing powders and fibers. Using these techniques, the authors explore the formation and roles of various multiphase interfaces. They consider the potential for enhancing performance and highlight related applications, particularly for powders and fibers.

The book details characteristics such as morphology, surface energetics, surface ionization, and electrokinetics for solid-gas, solid-rubber, solid-solid, solid-liquid, and biological interfaces. Areas of multidisciplinary interest also include the adsorption of biomolecules and biocompatibility of powders and fibers, nanoparticles and nanocomposites, biochips, and other biomedical applications, the measurement and significance of wettability, recent rheological data on mixes, and computer simulations used for visualizing complex solid surfaces.

As interest in the behavior and applications of powders and fibers steadily increases, Powders and Fibers: Interfacial Science and Applications offers a diverse approach that bridges fundamental aspects of interfacial science with applications of powders and fibers that is useful for newcomers as well as practitioners in related fields.

Lipid Analysis and Lipidomics: NewTechniques and Applications
Added 1/18/2008
Magdi MossobaJohn K.G. KramerJ. Thomas BrennaRichard McDonald
New methods for the analysis of edible oils, fats, and cellular lipids have recently been developed, presented at scientific meetings, and published in peer-reviewed journals. These methods apply to biological and food matrices, edible oils and fats, as well as cellular fats of pathogenic bacteria and spores, and will cover many research applications in lipidomics, food analysis, food safety, food security, and counter-terrorism. This text offers the lipid analyst essential analytical tools in the fields of chromatography, mass spectrometry, spectroscopy, magnetic resonance, and chemometrics. It also serves as a reference for recent developments in the rapidly evolving field of lipid methodologies.

Applied Pyrolysis Handbook, Second Edition
Added 4/7/2008
Thomas Wampler
Analytical pyrolysis allows scientists to use routine laboratory instrumentation for analyzing complex, opaque, or insoluble samples more effectively than other analytical techniques alone. Applied Pyrolysis Handbook, Second Edition is a practical guide to the application of pyrolysis techniques to various samples and sample types for a diversity of fields including microbiology, forensic science, industrial research, and environmental analysis.

This second edition incorporates recent technological advances that increase the technique's sensitivity to trace elements, improve its reproducibility, and expand its applicability. The book reviews the types of instrumentation available to perform pyrolysis and offers guidance for interfacing instruments and integrating other analytical techniques, including gas chromatography and mass spectrometry. Fully updated with new sample pyrograms, figures, references, and real-world examples, this edition also highlights new areas of application including surfactants, historical artifacts, and environmental materials.

This book illustrates how the latest advances make pyrolysis a practical, cost-effective, reliable, and flexible alternative for increasingly complex sample analyses. Applied Pyrolysis Handbook, Second Edition is an essential, one-stop guide for determining if pyrolysis meets application-specific needs as well as performing pyrolysis and handling the data obtained.

Natural Products from Plants, Second Edition
Added 2/15/2008
Leland CsekeAra KirakosyanPeter KaufmanSara WarberJames DukeHarry Brielmann
From medicinal, industrial, and culinary uses to cutting-edge laboratory techniques in modern research and plant conservation strategies, Natural Products from Plants, Second Edition reveals a vastly expanded understanding of the natural products that plants produce. In a single volume, this book offers a thorough inventory of the various types of plant-derived compounds. It covers their chemical composition, structure, and properties alongside the most effective ways to identify, extract, analyze, and characterize new plant-derived compounds.

The authors examine new information on the chemical mechanisms plants use to deter predators and pathogens, attract symbiotic organisms, and defend themselves against environmental stress-insights which are key for adapting such mechanisms to human health. Along with updated and revised information from the highly acclaimed first edition, the second edition presents seven new chapters and features more than 50% new material relating to plant constituents, natural product biochemistry, and molecular biology. The book incorporates in-depth treatment of natural product biosynthesis with new collection and extraction protocols, advanced separation and analytical techniques, up-to-date bioassays, as well as modern molecular biology and plant biotechnology for the production of natural products.

Unique in its breadth and coverage, Natural Products from Plants, Second Edition belongs on the shelf of interested researchers, policymakers, and consumers- particularly those involved in disease prevention, treatment, and pharmaceutical applications-who need a complete guide to the properties, uses, and study of plant natural products.

Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals, Second Edition
Added 4/7/2008
Donald MackayWan Ying ShiuKuo-Ching MaSum Chi Lee
Transport and transformation processes are key for determining how humans and other organisms are exposed to chemicals. These processes are largely controlled by the chemicals' physical-chemical properties. This new edition of the Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals is a comprehensive series in four volumes that serves as a reference source for environmentally relevant physical-chemical property data of numerous groups of chemical substances.

The handbook contains physical-chemical property data from peer-reviewed journals and other valuable sources on over 1200 chemicals of environmental concern. The handbook contains new data on the temperature dependence of selected physical-chemical properties, which allows scientists and engineers to perform better chemical assessments for climatic conditions outside the 20-25-degree range for which property values are generally reported.

This second edition of the Handbook of Physical-Chemical Properties and Environmental Fate for Organic Chemicals is an essential reference for university libraries, regulatory agencies, consultants, and industry professionals, particularly those concerned with chemical synthesis, emissions, fate, persistence, long-range transport, bioaccumulation, exposure, and biological effects of chemicals in the environment.

Thin Layer Chromatography in Chiral Separations and Analysis, Volume 98
Added 11/1/2007
Teresa KowalskaJoseph Sherma
Investigation and control of chirality, which is executed almost exclusively using chromatographic techniques, ranks among the most difficult separation tasks. As the first book devoted to this topic, Thin Layer Chromatography in Chiral Separations and Analysis presents updated information on this important field. The first part of this book discusses the problem of chirality in general and the technical possibilities of carrying out enantiomer separations in detail. Addressing significant application areas, the second part of the text provides a comprehensive overview of enantioseparations and densitometric analyses that have been successfully achieved using thin layer chromatography.

Analytical and Approximate Methods in Transport Phenomena
Added 4/7/2008
Marcio de Souza-Santos
On the job or in the field, when facing a problem with differential equations and boundary conditions, most likely you don't have time to read through several publications in search of a method that may or may not solve your problem. Organized for quick and easy access to practical solutions, Analytical and Approximate Methods in Transport Phenomena is a reference for the day-to-day problems encountered when working with variables in heat, mass, or momentum transfer.

This text is organized differently from usual resources on applied mathematics for engineers. First, it introduces a new classification system of the problem based on just three numbers, so locating the appropriate solution method is quick and easy. Second, the author presents mathematical methods with applications in mind, introducing examples, as well as common or possible solutions, before presenting any mathematical theory or method. This allows you to identify the issue you need to resolve, then apply the appropriate method to the problem at hand. The book also includes practical discussions of the consequences and applications of various solutions.

The book highlights mathematical methods as tools for solving practical problems, not as a primary objective. Its structure and focus on application, with just the right amount of mathematical rigor, makes it the most effective manual available for easily finding the analytical methods needed to solve transport problems.

Programming ArcObjects with VBA: A Task-Oriented Approach, Second Edition
Added 11/28/2007
Kang-Tsung Chang
If you're ready to take your knowledge of ArcGIS to the next level, then you need to learn how to work with ArcObjects. But with thousands of objects, properties, and methods, how can you ever hope to sort through the ArcObjects model diagrams?

The first edition of Chang's Programming ArcObjects with VBA: A Task-Oriented Approach gave us the answer. The author's task-oriented approach shows you how to sort through the massive ArcObjects collection by examining only the objects, properties, and methods you need to perform specific tasks.

What's new in the second edition?
This edition adds macros and explanations for the new Geoprocessing object introduced in ArcGIS 9.x. Instead of treating this new feature in separate chapters, the author incorporates Geoprocessing code into the existing chapters. The code appears conveniently in boxes that allow you to easily compare sample macros.

Get Started with Ready-to-Use Code
The companion CD-ROM contains 95 complete ArcObjects macros and 33 Geoprocessing macros, along with datasets to execute the code. Each program begins with a short usage description and a list of key properties and methods, followed by the listing and explanation of the code itself.

Regardless of your programming experience, Programming ArcObjects with VBA: A Task-Oriented Approach, Second Edition gives you the key to unlock the power and versatility of using ArcObjects to help you manage GIS activities.

Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies
Added 1/25/2008
H. John SmithClaire SimonsRobert E. Sewell
Research focused on protein folding, misfolding, and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era, where a number of orphan genes have been identified for which no clear function has yet been established. This research is starting to shed light on the molecular and biochemical basis of a number of neurodegenerative diseases of dramatic impact.

Protein Misfolding in Neurodegenerative Diseases: Mechanisms and Therapeutic Strategies addresses key issues concerning protein misfolding and aggregation in neurodegenerative diseases. Building on recent developments, including the recognition of protein misfolding as both a marker and a causal agent, the text presents the work of those who are actively pursuing more effective treatments, as well as preventative measures, and a possible cure. These include the use of molecular chaperones to control misfolding and novel pharmaceuticals, as well as the potential role of various inhibitors and NSAIDS.

A Comprehensive Multifaceted Examination of the Complex Causal Agents Implicated in Protein Misfolding

Divided into five sections, this groundbreaking text provides up-to-date accounts for Alzheimer’s, Parkinson’s, Huntington’s, Amyotrophic Lateral Sclerosis and Transmissible Spongiform Encephalitis. It also explores the highly likelihood that multiple factors, including oxidative stress, play a role in these complex diseases.

Oxide Surfaces
Added 12/7/2007
James Wingrave
A detailed treatment of information relating to fluid-oxide interfaces. It outlines methods for quantifying adsorption and desorption of polymeric and non-polymeric solutes at the gas- and solution-oxide interfaces. It also analyzes novel properties of oxide membranes and the synthesis and dissolution of oxide solids.

Computational Methods in Surface and Colloid Science
Added 12/7/2007
Malgorzata Borowko
This volume presents computer simulation methods and mathematical modelling of physical processes used in surface science research. It offers in-depth analysis of advanced theoretical approaches to behaviours of fluids in contact with porous, semiporous and nonporous solid surfaces. The book also explores interfacial systems for a wide variety of phenomena, including: absorption, flotation, osmosis, and colloidal stability.

Encyclopedic Handbook of Emulsion Technology
Added 12/7/2007
Johan Sjoblom
A discussion of fundamental characteristics, theories and applications for liquid-liquid colloidal dispersions. It profiles experimental and traditional measurement techniques in a variety of emulsified systems, including rheology, nuclear magnetic resonance, dielectric spectroscopy, microcalorimetry, video enhanced microscopy, and conductivity.

Current Practice of Gas Chromatography-Mass Spectrometry
Added 12/7/2007
Wilfried M.A. Niessen
This volume details the principles and instrumentation of gas chromatography-mass spectrometry (CG-MS), and outlines industrial, environmental, pharmaceutical, clinical, toxicological, forensic and food-related applications, revealing findings from the laboratories of 40 contributing scientists around the world using GC-MS in practice. It describes upstream and downstream applications of GC-MS in the petroleum industry and identifies chlorinated compounds in the environment with quadrupole ion-trap technology and high-resolution sector instruments.

Glycochemistry: Principles: Synthesis, and Applications
Added 12/7/2007
Peng George WangCarolyn Bertozzi
US, Canadian, and Chinese chemists summarize recent research into the synthesis, principles, and applications of carbohydrates for graduate students and researchers in carbohydrate chemistry, biochemistry, medicinal chemistry, and glycobiology. The topics include solid phase oligosaccharide synthesis, the chemical synthesis of bioactive steroidal saponins, the chemistry and biology of multi-valent saccharide displays, structures and mechanisms of action of aminoglycoside antibiotics, synthesizing glycosaminoglycans, glycosyltransferases in oligosaccharide synthesis, and metabolic substrate engineering as a tool for glycobiology Glycochemistry: Principles, Synthesis, and Applications presents methods used in the development of carbohydrate-based therapeutics. It highlights applications in chemical and enzymatic synthesis of complex carbohydrates, carbohydrate function, and carbohydrate-mediated biological recognition processes. There are practical examples on the development of carbohydrate-based pharmaceuticals and polymers for commercial use. The text also emphasizes the role of carbohydrates as key elements in modern molecular recognition processes.

Soil Sampling and Methods of Analysis, Second Edition
Added 12/14/2007
M.R. CarterE.G. Gregorich
Thoroughly updated and revised, this second edition of the bestselling Soil Sampling and Methods of Analysis presents several new chapters in the areas of biological and physical analysis and soil sampling. Reflecting the burgeoning interest in soil ecology, new contributions describe the growing number and assortment of new microbiological techniques, describe in-depth methods, and demonstrate new tools that characterize the dynamics and chemistry of soil organic matter and soil testing for plant nutrients. A completely new section devoted to soil water reviews up-to-date field- and laboratory-based methods for saturated and unsaturated soil hydraulic properties.

Retaining the easy-to-follow, "cookbook" style of the original, this second edition provides a compilation of soil analytical techniques that are fast, straightforward, and relatively easy-to-use. Heavily referenced, peer-reviewed contributions from approximately 150 specialists make this a practical manual and resource handbook that describes a wide array of methods, both conventional and cutting-edge, for analyzing the chemical, biological, biochemical, and physical properties of many different soil types. Including several "primer" chapters that cover the overall principles and concepts behind the latest techniques, the book presents sufficient detail on the materials and procedures to characterize the potential and limitation of each method. It covers recent improvements in methodology, outlines current methods, and characterizes the best methods available for selecting the appropriate analysis technique.

Promoting the research and practical application of findings in soil science, Soil Sampling and Methods of Analysis, Second Edition continues to be the most current, detailed, comprehensive tool for researchers and practitioners working with soil.

Anti-Angiogenic Functional and Medicinal Foods
Added 1/3/2008
Jack LossoFereidoon ShahidiDebasis Bagchi
The ability to regulate and manipulate the generation or remodeling of blood vessels is key to the successful treatment of many chronic diseases, both oncological and non-oncological. Several bioactive compounds present in human diets are now known to exert an inhibitive effect on the either the signaling or construction of new blood vessels. The identification and characterization of these anti-angiogenic molecules opens a new avenue for the research and production of functional and medicinal foods with far reaching implications for the food-based treatment of chronic degenerative disease.

Drawing from an extensive list of esteemed international contributors, Anti-Angiogenic Functional and Medicinal Foods explores the history and scope of the use of conventional foods, nutraceuticals, and health products in North America, Europe, the Middle East, Asia, India, Australia, and New Zealand. Recent advancements in proteomics, genomics, and toxicogenomics give us a far more detailed picture of the molecular basis of nutrition and systems toxicology. Explaining the role of angiogenesis in various chronic diseases, individual chapters consider endothelial cell responses, the mechanism of the angiogenic cascade, and the angiogenic function involved in tumors, cardiovascular disease, inflammatory arthritis, and obesity. A collection of chapters studies specific foods and their functional bioactive compounds such as the effects of edible berry anthocyanins, various Chinese medicinal foods, dietary flavonoids, probiotics, shark cartilage, EPA and DHA, and marine polysaccharides. The book concludes with a discussion of the challenges faced during the development and delivery of anti-angiogenic functional food products.

Presenting the current research and state of the science, Anti-Angiogenic Functional and Medicinal Foods provides researchers, scientists, clinical nutritionists, and oncologists with a valuable reference to this important and growing mode of therapy.

Interfacial Phenomena: Equilibrium and Dynamic Effects, Second Edition
Added 2/15/2008
Clarence MillerP. Neogi
Since the publication of the first edition of Interfacial Phenomena, the interest in interfaces and surfactants has multiplied, along with their applications. Experimental and theoretical advances have provided scientists with greater insight into the structure, properties, and behavior of surfactant and colloid systems.

Emphasizing equilibrium phenomena, flow, transport, and stability,
Interfacial Phenomena: Equilibrium and Dynamic Effects, Second Edition presents a concise and current summary of the fundamental principles governing interfacial interactions. This new edition features updated and expanded topics in every chapter. It highlights key experimental techniques that have expanded the scope of our understanding, such as in mass transfer, microstructure determination in colloidal dispersions, and surfactant-polymer interactions.

Interfacial Phenomena, Second Edition reflects the progress scientists have made in understanding the surface chemistry and interfacial dynamics of colloid and surfactant systems. The book also illustrates the growing applicability of these systems in a variety of fields including pharmaceuticals, cosmetics, detergents, paints, agricultural chemicals, and foods.

Seagrasses: Monitoring, Ecology, Physiology, and Management
Added 12/27/2007
Stephen Bortone
Seagrasses are becoming widely used as in situ indicators of the relative health and condition of subtropical and tropical estuarine ecosystems. To permit meaningful management of our estuaries, there is clearly a need to develop and refine ways of effectively monitoring and assessing seagrasses.
Seagrasses: Monitoring, Ecology, Physiology, and Management includes the peer-reviewed, written results of presentations made at a recent workshop that addressed this very issue. A total of 28 original research and review chapters are organized around four major themes: Ecology and Physiology, Monitoring and Trends, Management, and Restoration. Additional research study results, not completed at the time of the workshop, are also included as they are directly related to the topic of seagrass management ecology.
Overall, Seagrasses: Monitoring, Ecology, Physiology, and Management encompasses the latest research in seagrass management ecology to assist in the promotion of a dialogue between the research and environmental management communities. Not only will this work serve as a cornerstone for continued improvement in effectively monitoring the health and condition of near coastal waters, but also as a reference central to the premise that effective and efficient assessment of seagrasses will aid in estuarine ecosystem management.

Bitter Nemesis: The Intimate History of Strychnine
Added 12/27/2007
John Buckingham
Encouraged by the medicinal success of quinine, early 19th century scientists hoped strychnine, another plant alkaloid with remarkable properties, might also become a new weapon against disease. Physicians tried for over a century, despite growing evidence to the contrary, to treat everything from paralysis to constipation with it. But strychnine proved only to be disappointingly deadly-relegating its fate almost entirely to animal control, the dangerous adulteration of foods, and criminal exploits.

The NOTORIOUS and TRUE story of how a POISONOUS alkaloid...

Bitter Nemesis: The Intimate History of Strychnine presents a scholarly and compelling history of this fascinating chemical substance from its discovery to present times. A renowned editor for the Dictionary of Natural Products, Dr. John Buckingham fuses his eclectic interests into an extraordinary mix of original research spanning the realms of history, medicine, literature, chemistry, and forensics.

...Changed the course of HISTORY!

Uncovering details and logistics from the earliest experiments performed in an era when proper scientific trials for testing new drugs were still in their infancy, the author explores strychnine's trial-and-error contributions to scientific, medical, and forensic developments. He also investigates historical milestones and the perception of strychnine in popular culture-including criminal notoriety, accidental misuse, and new claims of strychnine's benefits that extend through to the present day.

Juxtaposing the real trials, mistrials, and persistent curiosity associated with one of history's most notorious pharmaceutical failures, Bitter Nemesis offers rare insight into the anarchic, yet inspired landscape, practices, and legacy of 19th century science.

Forensic Issues in Alcohol Testing
Added 12/27/2007
Steven Karch, MD, FFFLM
Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you need at an affordable price.

Forensic Issues in Alcohol Testing offers concise and focused information specific to the interests of forensic scientists and clinical and forensic toxicologists. It analyzes the acute effects of alcohol intoxication and the methods by which investigators can measure alcohol concentration in blood, urine, and breath. It considers extenuating circumstances affecting acute impairment by detailing the disposition and fate of alcohol in the body as well as the factors influencing absorption, distribution, and elimination. Specific chapters address difficulties in measuring and interpreting post-mortem alcohol concentrations due to poor quality of specimen, sampling site differences, and post-mortem diffusion or synthesis. Recent advances in biochemical testing make it possible to quantitate chronic alcohol ingestion, and the book analyzes the efficacy of these tests as evaluators of dependence or potential for dependence.

Hansen Solubility Parameters: A User's Handbook, Second Edition
Added 1/18/2008
Charles Hansen
Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including polymers, inorganic salts, and biological materials.

To update his groundbreaking handbook with the latest advances and perspectives, Charles M. Hansen has invited five renowned experts to share their work, theories, and practical applications involving HSPs. New discussions include a new statistical thermodynamics approach for confirming existing HSPs and how they fit into other thermodynamic theories for polymer solutions. Entirely new chapters examine the prediction of environmental stress cracking as well as absorption and diffusion in polymers. Highlighting recent findings on interactions with DNA, the treatment of biological materials also includes skin tissue, proteins, natural fibers, and cholesterol. The book also covers the latest applications of HSPs, such as ozone-safe “designer” solvents, protective clothing, drug delivery systems, and petroleum applications.

Presenting a comprehensive survey of the theoretical and practical aspects of HSPs, Hansen Solubility Parameters, Second Edition concludes with a detailed discussion on the necessary research, future directions, and potential applications for which HSPs can provide a useful means of prediction in areas such as biological materials, controlled release applications, nanotechnology, and self-assembly.

Functional Informatics in Drug Discovery
Added 1/18/2008
Sergey Ilyin
Integrating various technologies with informational systems provides vast improvements to the overall research and development that occur in the biopharmaceutical industry. One of the first books to explore this area, Functional Informatics in Drug Discovery examines all aspects of technology integration and information flow in a biopharmaceutical enterprise and outlines the specific technologies used at various stages of drug development.

With contributions from leaders in academia, information technology, and the pharmaceutical industry, each chapter illustrates how a particular area of biological science can benefit from the tools of informatics. The book first looks at intelligent automation, neurally based computational tools, and pharmacodynamic (PD) biomarkers. It then reviews a variety of novel technologies and approaches presently used in drug discovery at Johnson & Johnson. The text also describes how informatics can advance antibody technology and drug development for oncology. After focusing on forward genetic and reverse genetic strategies to identify relevant target genes for drug discovery, the book explains proteomic expression profiling and explores the application of laser microdissection in transcriptomics.

Taking a systematic approach, this volume examines the impact of informatics tools on various areas in biopharmaceuticals by presenting in-depth analyses of emerging trends and future opportunities.

Groundwater and the Environment: Applications for the Global Community
Added 1/18/2008
Igor ZektserLorne Everett
Historically, water has been treated as an inexhaustible resource. However, with the growth of population and development of industry and agriculture, freshwater demand has increased drastically, and its shortage felt in roughly 60% of the Earth. As early as 1931, renowned Russian scholar A.P. Karpansky wrote: "Water is not only a mineral resource, not only a means for developing agriculture. Water is a real culture bearer, it is a living blood, that creates life where there was none".

Groundwater and the Environment: Remediation Applications and the Global Community covers one of the most important ecological problems - the impact on the environment of intensive groundwater pumping out. Drawing on more than a quarter century of study, Zektser analyses and makes conclusions about groundwater exploitation throughout the world. He focuses on the close connection of groundwater to the environment - its affect on surface water streams, reservoirs, seas, landscapes, and vegetation.

The author demonstrates the importance of groundwater to the potable water supply, and its interaction with the environment. He stresses the significance of groundwater as a mineral resource. He provides techniques for assessing and mapping natural groundwater resources and develops these principles for studying water and hydrochemicals in coastal zones.

In the last twenty years, the global awareness of groundwater as one of the most important natural resources has grown. Any changes in the groundwater causes changes in the environment. Groundwater and the Environment: Remediation Applications and the Global Community increases your ability to predict the possible changes to the environment and to follow the principle: "When using - protect, when protecting - use!"

Handbook of Food Engineering, Second Edition
Added 2/1/2008
Dennis HeldmanDaryl Lund
As the demand for safe, nutritious, convenient foods continues to rise, and the capabilities of molecular biology and nutritional biochemistry continue to expand, the need for up-to-date engineering information becomes ever more critical. The application of innovative engineering concepts enables scientific breakthroughs to be utilized in the manufacture of the highest quality food products at the lowest possible cost.

Handbook of Food Engineering, Second Edition assembles the most recent information available for the efficient design and development of processes used in the manufacturing of food products, along with traditional background and fundamental information. In keeping with the comprehensive and informative style of the original, this second edition focuses on the thermophysical properties of food and the rate constants of change in food components during processing. It highlights the use of these properties and constants in process design.

Beginning with a review of the properties of food and food ingredients and the traditional unit operations associated with food manufacture, the book moves on to discuss specific points associated with freezing, concentration, dehydration, thermal processing, and extrusion. Key chapters cover basic concepts of the transport and storage of liquids and solids, as well as important topics in packaging, cleaning, and sanitation. New information on membrane processes addresses not only liquid concentration, but also other applications for membranes in food processing. The chapters on mass transfer in foods and food packaging have been extensively revised.

Delineating the concepts of engineering as they are applied to the latest advancements in food manufacture, Handbook of Food Engineering, Second Edition contributes to the evolution of food engineering as an interface between engineering and other food sciences.

Expert Witnessing and Scientific Testimony: Surviving in the Courtroom
Added 2/1/2008
Kenneth Cohen
Simply put, the primary role of the expert witness is to make clear and simple a complex technical or scientific issue. In practice, there are negative and positive aspects that must be considered before committing to the role. In a major case suing for big dollar amounts witnesses can expect to have their life history spread out like a roadmap for the world to see. On the other hand, finding and excavating the "smoking gun" piece of evidence can bring satisfaction far beyond any fees or hourly wage.

Based on the author's more than 30 years of experience as a successful expert witness, Expert Witnessing and Scientific Testimony: Surviving in the Courtroom demonstrates how to properly present scientific testimony and survive the onslaught of cross examination in court. Written in an engaging style, the book begins with introductory material to the world of litigation and the role and qualifications of the expert witness. It covers necessary legal protocols such as rules of evidence and procedure. Focusing on scientific testimony, the author demonstrates the use of scientific literature, presentation of testimony, and the language of lawyers. It addresses the courtroom experience with actual cases, experience, and pitfalls to illustrate procedure and strategy, cross-examination, and the exposure of personal history. Offering critical observations and judicial opinions, the book presents several exemplary civil, criminal, medical malpractice, and workers compensation cases. The author also includes his personal advice and tips on the business of expert witnessing. There is an extensive glossary of legal terms, detailed footnotes, and useful appendices summarizing code of conduct, paperwork, and examples of case reports.

Offering an insider's look at the labyrinthine world of litigation, Expert Witnessing and Scientific Testimony: Surviving in the Courtroom provides a guide for expert witnesses in today's legal environment.

Electrochemical Microsystem Technologies
Added 2/1/2008
J. Walter SchultzeTetsuya OsakaMadhav Datta
Driven by the electronics industry, electrochemical technology has rapidly evolved, finding increasing applications in microelectronics, batteries, sensors, materials science, industrial fabrication, corrosion, microbiology, neurobiology and medicine. Electrochemical Microsystem Technologies provides an overview of the technological status; the development of micropatternings and micro-biosensors; and the applications of micropower with electrochemical microsystems.
This book covers a wide spectrum of issues ranging from fundamental electrochemical processes to their applications in micro- and nanofabrication, microanalyses, microsensing, and their interaction with inorganic surfaces and biological systems. The editors provide comprehensive background to unique processes, such as the technological development of miniaturization, microfabrication, thin film deposition, etching, cleaning, planarization, and silicon processing technologies to introduce a wide range of applications in context.
More than 40 internationally recognized industry, research, and medical experts provide insight on the current status and future trends in their fields. They also highlight the impact of applying electrochemical microsystem technologies on industries such as storage and packaging; microelectronics, sensors, and portable electronics; machining, polishing, anodization, and plating technologies in heavy industries; biosensing, biological implant technology, and neurobiology; and cross-disciplinary integrated systems.
Electrochemical Microsystem Technologies is a valuable reference for graduate/postgraduate students, technologists, and researchers working in the field of electrochemical technology.

Physiology and Biochemistry of Sterols
Added 2/1/2008

Lipoxygenase and Lipoxygenase Pathway Enzymes
Added 2/1/2008

CRC Handbook of Liquid-Liquid Equilibrium Data of Polymer Solutions
Added 4/4/2008
Christian Wohlfarth
Thermodynamic data form the basis for separation processes used in different fields of science and industry, from specialty chemicals to foods and pharmaceuticals. One obstacle to developing new production processes, products, or optimization is the lack, or inaccesibility, of experimental data related to phase equilibrium.

The CRC Handbook of Liquid-Liquid Equilibrium Data of Polymer Solutions provides a thorough and up-to-date compilation of experimental liquid-liquid equilibrium (LLE) data and their original sources. The handbook contains more than 1200 data sets, including 810 binary systems, 325 ternary systems, and 25 quaternary (or higher) systems. Arranged in a consistent format, it provides convenient access to cloud-point and coexistence data as well as upper and lower critical solution temperatures and important demixing data for each system.

Written by a well-known scientist in the field of polymer solution thermodynamics who is also a respected contributor to the Handbook of Chemistry and Physics, this volume is an excellent companion to the author’s substantial compilations of thermodynamic data for binary polymer solutions, copolymer solutions, aqueous polymer solutions, and polymer solutions at elevated temperatures.

Process Chemistry of Lubricant Base Stocks
Added 3/14/2008
Thomas Lynch
Advances in processing methods are not only improving the quality and yield of lubricant base stocks, they are also reducing the dependence on more expensive crude oil starting materials.  Process Chemistry of Lubricant Base Stocks provides a comprehensive understanding of the chemistry behind the processes involved in petroleum base stock production from crude oil fractions.

This book examines hydroprocessing technologies that, driven by the demand for higher performance in finished lubricants, have transformed processing treatments throughout the industry. The author relates the properties of base stocks to their chemical composition and describes the process steps used in their manufacture. The book highlights catalytic processes, including hydrocracking, hydrofinishing, and catalytic dewaxing. It also covers traditional solvent-based separation methods used to remove impurities, enhance performance, and improve oxidation resistance. The final chapters discuss the production of Food Grade white oils and paraffins and the gas-to-liquids processes used to produce highly paraffinic base stocks via Fischer-Tropsch chemistry.

Process Chemistry of Lubricant Base Stocks provides historical and conceptual background to the technologies used to make base stocks, thorough references, and a unique emphasis on chemical, not just engineering, aspects of lubricant processing—making this book an ideal and practical reference for scientists across a wide range of disciplines.

Electrochemistry of Zirconia Gas Sensors
Added 2/8/2008
Serge Zhuiykov
The first book to present a detailed analysis of the electrochemistry, development, modeling, optimization, testing, and technology behind modern zirconia-based sensors, Electrochemistry of Zirconia Gas Sensors explores how to tailor these sensors to meet specific industrial needs. The book addresses a range of different stages of development in zirconia-based sensors for gaseous and molten metal environments, focusing on an accessible form from analysis of interaction at the measuring environment-zirconia sensor interface to reliability testing of the sensors.

The coverage highlights different fundamental aspects of electrochemistry and physical chemistry of zirconia, mathematical modeling, optimization parameters, and structures of the electrode materials. The author highlights the factors that determine high sensitivity, critically reviews the limitations of current technologies, and surveys the needs and possibilities of future developments. He covers technologies for vacuum-tight joining zirconia to ceramic insulators and sensor construction materials as well as sensor design and concepts of the total-NOx sensor based on mixed potential. The book includes a critical overview of existing technologies of zirconia gas sensors including nanotechnology.

This book fills the gap between pure academic research of the zirconia-based gas sensors, explaining the influence of the double electrical layer on the sensor output signal and the applied, technological, down-to-earth approaches adopted by the vast majority of the industrial companies working in this field. Providing guidance on how to organize a testing program of gas sensors, the book allows readers to look forward in evaluating future trends in the zirconia gas sensors development.

Dictionary of Marine Natural Products with CD-ROM
Added 2/15/2008
John BluntMurray G. Munro
Driven by the vast, yet largely unexplored, potential of bioactive organisms in the ocean and improvements in analytical techniques to facilitate their research, natural products scientists face an increasing need for single-source reference cataloging the current knowledge and state-of-the-science regarding marine natural products.

Dictionary of Marine Natural Products with CD-ROM presents a comprehensive resource for more than 25,000 known natural products drawn from marine organisms. Following a similar format to the Chapman and Hall Chemical Database, this dictionary indexes each product by chemical name, CAS registry number, and compound type. Documenting all known marine natural products, each entry includes the biological source, chemical structure, physical properties, biological activity, and literature references for each compound. An accompanying CD-ROM is fully text and structure-searchable and enables unique access to this valuable resource. The editors, John Blunt and Murray Munro, both pioneers in the field, also provide an introductory monograph that describes structural compound types and marine organisms.

Marine organisms offer a delicate, yet plentiful source for a vast array of novel products whose unique structural features make them suitable drug candidates, pesticides, marine anti-fouling agents, and more. The
Dictionary of Marine Natural Products Web Version gives researchers a new tool for developing pharmaceutical and chemical applications of marine natural products.

Handbook of Near-Infrared Analysis, Third Edition
Added 2/29/2008
Donald BurnsEmil Ciurczak
Fast, inexpensive, and easy-to-use, near-infrared (NIR) spectroscopy can be used to analyze small samples of virtually any composition. The Handbook of Near Infrared Analysis, Third Edition explains how to perform accurate as well as time- and cost-effective analyses across a growing spectrum of disciplines.

Presenting nearly 50% new and revised material, this thoroughly updated edition incorporates the latest advances in instrumentation, computerization, calibration, and method development in NIR spectroscopy. The book underscores current trends in sample preparation, calibration transfer, process control, data analysis, and commercial NIR instrumentation. New chapters highlight novel applications including the analysis of agro-forestry products, polymers, blood, and control serum. They also cover NIR spectra, process analytical technologies (PAT), quantitative and qualitative analyses for nutraceuticals, NIR photography uses in medicine, and counterfeit detection methods for pharmaceuticals and currency.

Offering the most complete single-source guide of its kind, the Handbook of Near Infrared Analysis, Third Edition continues to offer practicing chemists and spectroscopists an unparalleled combination of theoretical foundations, cutting-edge applications, and practical experience provided firsthand by more than 60 experts in the field.

Handbook of Acid-Base Indicators
Added 2/29/2008
R. Sabnis
While acid-base indicators continue to find new applications in an ever-widening range of scientific disciplines, there is no current book that focuses entirely on the subject, nor one that brings together the relevant advances that have evolved over the last three decades. The Handbook of Acid-Base Indicators compiles the most up-to-date, comprehensive information on over 200 water-based and solvent-based indicators into a single source.

Organized alphabetically, entries include: common name, other names, CA index name, CAS registry number, Merck index number, chemical structure, chemical/dye class, molecular formula, molecular weight, pH range, color change at pH, pKa, physical form, solubility, UV-visible (Lambda-max), melting point, and boiling point. This resource also offers unique coverage including protocols for synthesizing indicator compounds; data relating to adverse effects, toxicity, and safety; and major applications for each indicator.

The Handbook of Acid-Base Indicators contains practical information for widespread applications that include semiconductors, displays, nanotechnology, OLEDs, fuel cells, sensors, security, surface coatings, adhesives, insecticides, agricultural chemicals, textiles, packaging, cosmetics, personal care products, pharmaceuticals, and the detection and treatment of disease.

Practical Guide to Interpretive Near-Infrared Spectroscopy
Added 2/29/2008
Jerry WorkmanLois Weyer
Containing focused, comprehensive coverage, Practical Guide to Interpretive Near-Infrared Spectroscopy gives you the tools necessary to interpret NIR spectra. The authors present extensive tables, charts, and figures with NIR absorption band assignments and structural information for a broad range of functional groups, organic compounds, and polymers. They include visual spectral representation of all major compound functional groupings and NIR frequency ranges. Organized by functional group type and chemical structure, based on standard compound classification, the chapters are easy to follow and understand. The use of Molecular Formula and CAS Number indexing prevents the confusion that can occur when using only common chemical names to identify compounds.

Interpretive spectroscopy provides a basis for the establishment of cause-and-effect relationships between spectrometer response and the chemical properties of the samples. While many books available on NIR cover a range of applications and topics from a broad perspective, most of them barely touch on structure correlation and interpretation of spectra. The first, and arguably the only, book to tackle this intriguing and challenging area, Practical Guide to Interpretive Near-Infrared Spectroscopy presents the most detailed discussion of the subject to date.

Industrial Applications of Single Cell Oils
Added 4/10/2008

Environmental Degradation and Transformation of Organic Chemicals
Added 3/14/2008
Alasdair NeilsonAnn-Sofie Allard
Addressing the persistent environmental threat of organic chemicals with a fresh approach to degradation and transformation processes, Environmental Degradation and Transformation of Organic Chemicals examines a wide range of compounds as well as abiotic and microbiological reactions mediated by microorganisms. The book emphasizes the pathways used and the broad classes of enzymes involved. It provides an overview of experimental procedures with detailed coverage of the organic compounds that are considered to be xenobiotics.

The book begins by providing a broad perspective on abiotic and biotic reactions, including the significance of a range of environmental determinants. The following chapters briefly introduce experimental procedures and emphasize those procedures for establishing the structure of metabolites using isotopes and physical methods. Next, the authors outline details of biochemical reactions involved in the biodegradation of the major groups of aliphatic, carbocyclic aromatic, and heterocyclic compounds. They end with coverage of bioremediation that has attracted increasing concern because of the hazard presented by the disposal of unwanted chemicals or by-products from their manufacture.

Broad and comprehensive, this book provides a cohesive treatment of the subject. It contains an extensive set of literature references and numerous illustrative figures. The authors use a mechanistic approach with emphasis on the pathways, and the principles that emerge provide a guide not only for specific compounds but also for those having a more remote structural resemblance.

Thin Layer Chromatography in Phytochemistry
Added 3/28/2008
Monika Waksmundzka-HajnosJoseph ShermaTeresa Kowalska
Thin layer chromatography (TLC) is increasingly used in the fields of plant chemistry, biochemistry, and molecular biology. Advantages such as speed, versatility, and low cost make it one of the leading techniques used for locating and analyzing bioactive components in plants.

Thin Layer Chromatography in Phytochemistry is the first source devoted to supplying state-of-the-art information on TLC as it applies to the separation, identification, quantification, and isolation of medicinal plant components. Renowned scientists working with laboratories around the world demonstrate the applicability of TLC to a remarkable diversity of fields including plant genetics, drug discovery, nutraceuticals, and toxicology.

Elucidates the role of plant materials in the pharmaceutical industry...

Part I provides a practical review of techniques, relevant materials, and the particular demands for using TLC in phytochemical applications. The text explains how to determine the biological activity of metabolites and assess the effectiveness of herbal medicines and nutritional supplements. Part II concentrates on TLC methods used to analyze specific plant-based metabolite classes such as carbohydrates, proteins, alkaloids, flavonoids, terpenes, etc. Organized by compound type, each chapter discusses key topics such as sample preparation, plate development, zone detection, densitometry, and biodetection.

Demonstrates practical methods that can be applied to a wide range of disciplines...

From identification to commercial scale production and quality control, Thin Layer Chromatography in Phytochemistry is an essential bench-top companion and reference on using TLC for the study of plant-based bioactive compounds.

Applications of Environmental Aquatic Chemistry: A Practical Guide, Second Edition
Added 3/28/2008
Eugene Weiner
Professionals and students who come from disciplines other than chemistry need a concise, yet reliable guide that explains key concepts in environmental chemistry, from the fundamental science to the necessary calculations for applying them. Updated and reorganized, Applications of Environmental Aquatic Chemistry: A Practical Guide, Second Edition provides the essential background for understanding and solving environmental chemistry problems that arise most frequently.

Diverse and self-contained chapters offer a centralized and easily navigable framework for finding useful data tables that are ordinarily scattered throughout the literature. The book explains how to interpret the significance of water quality data, including expanded tables with water quality parameters and chemicals that relate to water quality. It also contains EPA water use classifications and describes treatment methods for industrial, municipal, and agricultural waste discharges.

Worked examples provide step-by-step details for frequently used calculations, drawing on case histories from real-world environmental applications. Chapters also offer tools for calculating quick estimates of important quantities and practice problems that apply the principles to different conditions. This practical guide provides an ideal basis for self-study as well as short courses involving the movement and fate of contaminants in the environment.

Chemistry and Physics of Carbon, Volume 30
Added 4/7/2008
Ljubisa Radovic
Written by distinguished researchers in carbon, the long-running Chemistry and Physics of Carbon series provides a comprehensive and critical overview of carbon in terms of molecular structure, intermolecular relationships, bulk and surface properties, and their behavior in an amazing variety of current and emerging applications, ranging from nanotechnology to environmental remediation. Volume 30 not only retains the high-quality content and reputation of previous volumes, but also complements them with reliable and timely coverage of the latest advances in the field.

The first chapters analyze progressive approaches to controlling more precisely the structure, morphology, and surface properties of novel activated carbons. They cover methods using activating agents such as alkaline hydroxides as well as endo- and exotemplates made from zeolites, silica, and colloidal crystals. The third chapter examines techniques for characterizing carbon surface chemistry, including electrochemical, spectroscopic, and chromatographic methods. The fourth and final chapter compares the virtues of exfoliated graphite, carbonized fir fibers, carbon fiber felt, and charcoals in solving oil spill problems, a matter of increasing environmental concern.

Emphasizing key experimental results, practical aspects, and cutting-edge applications in every chapter, Volume 30 is a vital resource for those developing new technologies such as drug delivery, adsorbents for oil/chemical spills, materials processing, high-performance nanocarbons, and energy storage and conversion devices, including lithium ion batteries, supercapacitors, and fuel cells.

Micro- and Nanostructured Multiphase Polymer Blend Systems: Phase Morphology and Interfaces
Added 4/9/2008
Charef HarratsSabu ThomasGabriel Groeninckx
Micro- and Nanostructured Multiphase Polymer Blend Systems: Phase Morphology and Interfaces focuses on the formation of phase morphology in polymer blends and copolymers and considers various types of blends including thermosets, thermoplastics, thermoplastic vulcanizates, and structured copolymers. The book carefully debates the processing, rheology, and crystallization aspects of the phase morphology of polymer blends.

The text surveys theory, characterization, processing, and experimental aspects of phase morphology development and design of polymer blends. It examines the adhesion of polymer–polymer interfaces in immiscible polymer blends and the different ways by which nanostructures may be generated in thermosetting polymers. The book analyzes the polymerization process and the dynamic vulcanization of multicomponent polymer blends and the crystallization behavior occurring in blends with a confined morphology. It also discusses the structure–rheology relationship in compatibilized blends, the effects of elasticity on the structure development, and the rheological response in concentrated blends.

Micro- and Nanostructured Multiphase Polymer Blend Systems examines the current state of the art, challenges, and future prospects in the field of polymer blends. The handpicked selection of topics and expert contributors makes this survey of phase morphology in polymer blends an outstanding resource for anyone involved in the field of polymer materials design.

Advances in Chromatography: Volume 45
Added 4/8/2008
Eli GrushkaNelu Grinberg
For more than four decades, scientists and researchers have relied on the Advances in Chromatography series for the most up-to-date information on a wide range of developments in chromatographic methods and applications. Volume 45 of this authoritative series once again compiles the work of expert contributors in order to present timely and cutting-edge reviews on a variety of related topics.

This volume focuses on applying various chromatographic techniques to combinatorial methods and high-throughput analyses. The authors address various limitations to traditional techniques and present developments that enable scientists to analyze a higher volume of smaller molecules under high-throughput conditions more efficiently. Other practical topics include discussions of selection criteria for using alternative solvents and reagents, minimum requirements for utilizing readily available instrumentation and methods for new applications, the use of high-throughput purification for obtaining higher quality leads, and new chromatographic data on organic endocrine disrupters.

Advances in Chromatography: Volume 45 provides a good starting point to gain quick and up-to-date knowledge of the field and its most recent developments. Each author's clear presentation of topics and vivid illustrations make the material accessible and engaging to a variety of chemists with different levels of technical skill.

Chemical Process Performance Evaluation
Added 4/8/2008
Ali CinarAhmet PalazogluFerhan Kayihan
The latest advances in process monitoring, data analysis, and control systems are increasingly useful for maintaining the safety, flexibility, and environmental compliance of industrial manufacturing operations.
Focusing on continuous, multivariate processes, Chemical Process Performance Evaluation introduces statistical methods and modeling techniques for process monitoring, performance evaluation, and fault diagnosis.

This book introduces practical multivariate statistical methods and empirical modeling development techniques, such as principal components regression, partial least squares regression, input-output modeling, state-space modeling, and modeling process signals for trend analysis. Then the authors examine fault diagnosis techniques based on episodes, hidden Markov models, contribution plots, discriminant analysis, and support vector machines. They address controller process evaluation and sensor failure detection, including methods for differentiating between sensor failures and process upset. The book concludes with an extensive discussion on the use of data analysis techniques for the special case of web and sheet processes. Case studies illustrate the implementation of methods presented throughout the book.

Emphasizing the balance between practice and theory, Chemical Process Performance Evaluation is an excellent tool for comparing alternative techniques for process monitoring, signal modeling, and process diagnosis. The unique integration of process and controller monitoring and fault diagnosis facilitates the practical implementation of unified and automated monitoring and diagnosis technologies.

Instrument Engineers' Handbook, Fourth Edition, Volume Two: Process Control and Optimization
Added 4/8/2008
Béla Lipták
The latest update to Bela Liptak's acclaimed "bible" of instrument engineering is now available. Retaining the format that made the previous editions bestsellers in their own right, the fourth edition of Process Control and Optimization continues the tradition of providing quick and easy access to highly practical information. The authors are practicing engineers, not theoretical people from academia, and their from-the-trenches advice has been repeatedly tested in real-life applications. Expanded coverage includes descriptions of overseas manufacturer's products and concepts, model-based optimization in control theory, new major inventions and innovations in control valves, and a full chapter devoted to safety. With more than 2000 graphs, figures, and tables, this all-inclusive encyclopedic volume replaces an entire library with one authoritative reference. The fourth edition brings the content of the previous editions completely up to date, incorporates the developments of the last decade, and broadens the horizons of the work from an American to a global perspective.

Cryogenic Engineering, Second Edition
Added 4/9/2008
Thomas Flynn
Written by an engineering consultant with over 48 years of experience in the field, this Second Edition provides a reader-friendly and thorough discussion of the fundamental principles and science of cryogenic engineering including the properties of fluids and solids, refrigeration and liquefaction, insulation, instrumentation, natural gas processing, and safety in cryogenic system design.

Process Chemistry in the Pharmaceutical Industry, Volume 2: Challenges in an Ever Changing Climate
Added 4/8/2008
Kumar GadamasettiTamim Braish
As pharmaceutical companies strive to develop safer medicines at a lower cost, they must keep pace with the rapid growth of technology and research methodologies. Defying the misconception of process chemistry as mere scale-up work, Process Chemistry in the Pharmaceutical Industry, Vol. 2: Challenges in an Ever Changing Climate explores novel applications of synthetic, physical, and analytical chemistry in drug discovery and development. It offers an accurate depiction of the most up-to-date process research and development methods applied to synthesis, clinical trials, and commercializing drug candidates.

The second installment in this progressive series, this volumereviews the latest breakthroughs to advance process chemistry, including asymmetric synthesis, crystallization, morphology, enzymatic intervention, green chemistry, macromolecules (monoclonal antibodies, biological molecules, polymers), enantioselectivity, organometallic chemistry, process analytical tools, chemical engineering controls, regulatory compliance, and outsourcing/globalization. It explores new approaches to synthetic processes, examines the latest safety methods and experiment design, and suggests realistic solutions to problems encountered in manufacturing and process development. Significant topics include atom economy, ease of synthesis, instrumentation, automization, quality control, cost considerations, green practices, and future trends.

Jointly edited by the founder/president of Delphian Pharmaceuticals and the director of Chemical R&D at Pfizer, this book brings together contributions byreputed scientists, technologists, engineers, and professors from leading academic institutions, such as the Imperial College, UK, the University of Tokyo, ETH, Switzerland, the International University at Bermen, Germany, and the University of Connecticut, USA, and from principal pharmaceutical companies that include Merck, Bristol Myers Squibb, Pfizer, Novartis, Eli Lilly, Astrazeneca and DSM.

Carbon Monoxide and Cardiovascular Functions
Added 4/11/2008
Rui Wang
Akin to nitric oxide, carbon monoxide (CO) was initially viewed as a pure toxic gas, yet it has been recently demonstrated to be an important endogenous molecule of gas that has profound physiological and pathophysiological effects on the cardiovascular system. In spite of the growing understanding achieved in this field, until now a comprehensive book summarizing the extraordinary advances in the research of the cardiovascular effects of CO has not been available.

Carbon Monoxide and Cardiovascular Functions responds to the vexing challenges and exciting opportunities that confront researchers and clinicians studying the biological roles of CO in the cardiovascular system. This book presents many never-before-published results including the first case of human CO deficiency. It also discusses disorders where the cardiovascular effects of CO might have been altered, including hypertension, diabetes, stroke, and ischemic heart damage.

A product of the collected knowledge of internationally respected scientists, this book serves as a standard reference summarizing recent developments, scientific controversies, and future directions in the study of the biological actions of CO on the cardiovascular system. By covering both ancient and state-of-the-art methodologies in great detail, Carbon Monoxide and Cardiovascular Functions, affords a rapid mastery of the powerful new advances in CO study.

Geological and Soil Evidence: Forensic Applications
Added 4/11/2008
Kenneth Pye
The forensic potential of geological and soil evidence has been recognized for more than a century, but recently these types of evidence are used much more widely as an investigative intelligence tool and as evidence in court. There is, however, still a poor understanding of the potential value and the limitations of geological and soil evidence among the forensic science and wider legal communities.

Geological and Soil Evidence: Forensic Applications provides an authoritative introduction to the nature and properties of geological and soil materials that may be used as trace evidence and the techniques used to analyze and evaluate them. It emphasizes the use of geoscience in forensic analyses, including geophysical, meteorological, and geomorphological data. This inclusive book covers material types and analytical strategies used in examining both the common components of geological evidence, such as rocks, dusts, minerals, spores, and microfossils, as well as anthropogenic particles like pottery and brick. It instructs on particle characterization based on physical, chemical, and mineralogical traits such as color, shape, density, and elemental and isotopic composition. It also explains sampling and handling procedures particular to criminalistics and introduces analysis, evaluation, and decision-making practices based on statistical significance and the weighing of different types of evidence. Discussions of basic principles are supported and enhanced with numerous case studies that tie methods of analysis to specific forensic applications. Examples are drawn from the author's own experience as well as the wider scientific literature.

Accessible enough for readers with limited scientific knowledge and informative enough for scientists interested in forensic applications, Geological and Soil Evidence: Forensic Applications is a comprehensive reference for the current knowledge of forensic geology and soil science.